Searchable abstracts of presentations at key conferences in endocrinology

ea0016p596 | Paediatric endocrinology | ECE2008

The superoxide dismutase and lipid peroxide in children with Down syndrome and congenital heart disease

Wojcik Elzbieta , Barg Ewa , Gromkowska Malgorzata , Maslowska Ewa , Wikiera Beata , Kalita Danuta , Gamian Elzbieta , Turczyn Barbara , Skoczynska Anna

Metabolic disturbances occur more often in patients with Down Syndrome (DS, trisomy 21) than in the health population.Superoxide dismutase (SOD-1), the main enzyme in the antioxidative system, is coded on chromosome 21. Disturbances in the antioxidative system may play a major role in the development of complications of CHD with arterio-venous shunt.The aim was to evaluate the activity of SOD-1 and concentration of LPO in children ...